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Article

Nickel reactivity and filaggrin null mutations--evaluation of the filaggrin bypass theory in a general population.

Contact dermatitis - 1 Jan 2011

Ross-Hansen Katrine, Menné Torkil, Johansen Jeanne D, Carlsen Berit C, Linneberg Allan, Nielsen Niels H, Stender Steen, Meldgaard Michael, Szecsi Pal B, Thyssen Jacob P

Abstract excerpt

BACKGROUND: It was recently shown that filaggrin null mutation carrier status was associated with nickel allergy and self-reported intolerance to costume jewellery. Because of the biochemical characteristics of filaggrin, it may show nickel barrier properties in the stratum corneum. OBJECTIVES: To investigate whether subjects with filaggrin null mutations report nickel dermatitis at an earlier age than wild-type...

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Identifiers

PMID: 21166815
DOI: 10.1111/j.1600-0536.2010.01815.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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