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[FILAGGRIN GENE NULL-MUTATIONS AND ATOPIC DISEASES].

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti - 1 Jan 2015

Pipinić I Sabolić, Macan J

Abstract excerpt

Null-mutations which cause loss of function of the gene encoding filaggrin (FLG) have been strongly linked to the development of atopic disorders, predominantly atopic eczema/dermatitis syndrome (AEDS). Filaggrin plays a key role in epidermal barrier function by upholding epidermal structure and moisturization. Up to now, around 40 variants of FLG null-mutations have been genotyped among different world...

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Source

Identifiers

PMID: 29087092

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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