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Article

Overexpression of Prohibitin 2 Protein is Associated with Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia.

Annals of laboratory medicine - 1 Sept 2022

Lee Young Eun, Lim Ha Jin, Park Ju Heon, Kim Hye Ran, Kang Min-Gu, Cho Young Kuk, Shin Jong Hee, Shin Myung Geun

Abstract excerpt

Cytogenetically normal acute myeloid leukemia (CN-AML) accounts for 40%-50% of all AML cases. Despite advances in understanding the molecular pathophysiology of CN-AML, its clinical outcome remains unsatisfactory and unpredictable. To investigate its clinical implication in CN-AML, we measured the expression of prohibitin 2 (PHB2) using immunohistochemical staining (IHCS) of paraffin-embedded bone marrow sections...

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Identifiers

PMID: 35470276
DOI: 10.3343/alm.2022.42.5.585
PMCID: PMC9057826

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