Article
BAALC gene expression tells a serious patient outcome tale in NPM1-wild type/FLT3-ITD negative cytogenetically normal-acute myeloid leukemia in adults.
Blood cells, molecules & diseases - 1 Jul 2022
Verma Deepak, Kumar Rajive, Ali M Shadab, Singh Jay, Arora Mohit, Singh Inder, Kumari Sarita, Bakhshi Sameer, Sharma Atul, Palanichamy Jayanth Kumar, Tanwar Pranay, Singh Amar Ranjan, Chopra Anita
Abstract excerpt
Acute myeloid leukemia with normal cytogenetics (CN-AML) is the largest group of AML patients which is associated with a variegated patient outcome. Multiple molecular markers have been used to risk-stratify these patients. Estimation of expression of BAALC gene (Brain and Acute Leukemia, Cytoplasmic) mRNA level is one of the predictive markers which has been identified in multiple studies. In this study, we...
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