Article
Genetic abnormalities in acute myelogenous leukemia with normal cytogenetics.
Current hematologic malignancy reports - 1 Apr 2008
Wald David, Vermaat Johanna M, Peleg Gil, Tse William
Abstract excerpt
Acute myelogenous leukemia (AML) results from a differentiation block of hematopoietic progenitor cells along with uncontrolled proliferation. The cytogenetic abnormality at initial diagnosis is the single most important prognostic factor classifying AML patients into three prognostic categories: favorable, intermediate, and poor risk. Currently, favorable-risk AML patients are usually treated with contemporary...
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