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Article

TET2 gene mutation is unfavorable prognostic factor in cytogenetically normal acute myeloid leukemia patients with NPM1+ and FLT3-ITD - mutations.

International journal of hematology - 1 Jul 2014

Tian Xiaopeng, Xu Yang, Yin Jia, Tian Hong, Chen Suning, Wu Depei, Sun Aining

Abstract excerpt

Cytogenetically normal acute myeloid leukemia (cn-AML) is a group of heterogeneous diseases. Gene mutations are increasingly used to assess the prognosis of cn-AML patients and guide risk-adapted treatment. In the present study, we analyzed the molecular genetics characteristics of 373 adult cn-AML patients and explored the relationship between TET2 gene mutations or different genetic mutation patterns and...

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Source

Identifiers

PMID: 24859829
DOI: 10.1007/s12185-014-1595-x

Genes

TET2
FLT3
NPM1
ASXL1
CBL
IDH1
IDH2
KIT
NRAS
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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