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Article

Prognostic significance of combined BAALC and MN1 gene expression level in acute myeloid leukemia with normal karyotype.

International journal of laboratory hematology - 1 Jun 2021

Marjanovic Irena, Karan-Djurasevic Teodora, Kostic Tatjana, Virijevic Marijana, Vukovic Nada Suvajdzic, Pavlovic Sonja, Tosic Natasa

Abstract excerpt

INTRODUCTION: Acute myeloid leukemia with normal karyotype (AML-NK) is the largest group of AML patients with very heterogeneous disease outcome. In order to ensure more precise risk stratification new molecular markers have been introduced, like expression level for BAALC (Brain and Acute Leukemia, Cytoplasmic) and MN1 (Meningioma 1) genes. METHODS: In this study, we investigated expression level of both genes...

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PMID: 33242229
DOI: 10.1111/ijlh.13405

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