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Article

Phospholipase C Beta 2 Protein Overexpression Is a Favorable Prognostic Indicator in Newly Diagnosed Normal Karyotype Acute Myeloid Leukemia.

Annals of laboratory medicine - 1 Jul 2021

Park Mi Suk, Lee Young Eun, Kim Hye Ran, Shin Jong Hee, Cho Hyun Wook, Lee Jun Hyung, Shin Myung Geun

Abstract excerpt

Phospholipase C beta 2 (PLC-β2) regulates various essential functions in cell signaling, differentiation, growth, and mobility. We investigated the clinical implications of PLC-β2 protein expression in newly diagnosed normal karyotype acute myeloid leukemia (NK-AML). The PLC-β2 expression status in bone marrow tissues obtained from 101 patients with NK-AML was determined using semiquantitative...

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Identifiers

PMID: 33536360
DOI: 10.3343/alm.2021.41.4.409
PMCID: PMC7884198

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