Article
BP1 overexpression is associated with adverse prognosis in de novo acute myeloid leukemia.
Leukemia & lymphoma - 1 Jan 2016
Zhou Jing-dong, Yang Jing, Guo Hong, Deng Zhao-qun, Wen Xiang-mei, Yang Lei, Yin Jia-yu, Xiao Gao-fei, Lin Jiang, Qian Jun
Abstract excerpt
To investigate DLX4 isoforms expression and their clinical significance in acute myeloid leukemia (AML). DLX4 transcript variant 1 (BP1) expression was significantly up-regulated in AML patients compared with normal controls. However, DLX4 transcript variant 2 (DLX7) was significantly down-regulated in AML patients. Both in the overall AML and the non-M3 AML cohorts, those patients with high BP1 expression...
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