Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of PIK3CA Mutation Concordance and Frequency in Primary and Different Distant Metastatic Sites in Breast Cancer.

Cancer research and treatment - 1 Jan 2023

Park Jieun, Cho Soo Youn, Chang Eun Sol, Sung Minjung, Song Ji-Young, Jung Kyungsoo, Kim Sung-Su, Shin Young Kee, Choi Yoon-La

Abstract excerpt

PURPOSE: The purpose of this study was to investigate the concordance rate of PIK3CA mutations between primary and matched distant metastatic sites in patients with breast cancer and to verify whether there are differences in the frequency of PIK3CA hotspot mutations depending on the metastatic sites involved. MATERIALS AND METHODS: Archived formalin-fixed paraffin-embedded (FFPE) specimens of primary breast and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Breast Cancer Therapies
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Treatment and Pharmacology

Share to Class I Phosphatidylinositol 3-Kinases

Share to Mutation

Share to PI3K/AKT/mTOR signaling in cancer

Source

Open in PubMed Open full text

Identifiers

PMID: 35468270
DOI: 10.4143/crt.2022.001
PMCID: PMC9873343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of PIK3CA Mutation Concordance and Frequency in Primary and Different Distant Metastatic Sites in Breast Cancer.PMID 35468270Read ↗

Frequency of genetic alterations differs in advanced breast cancer between metastatic sites.Semantic proximity Read ↗

Discordance of PIK3CA mutational status between primary and metastatic breast cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in Breast cancer among Indian Population.Semantic proximity Read ↗

Circulating PIK3CA mutation detection at diagnosis in non-metastatic inflammatory breast cancer patients.Semantic proximity Read ↗

Discordance of PIK3CA and TP53 Mutations Between Breast Cancer Brain Metastases and Matched Primary TumorsSemantic proximity Read ↗

Analysis of PIK3CA mutations in the primary and recurrent tumors of hormone receptor positive/human epidermal growth factor receptor 2 negative breast cancer.Semantic proximity Read ↗

Use of Liquid Biopsy to Detect PIK3CA Mutation in Metastatic Breast Cancer.Semantic proximity Read ↗

PIK3CA mutation profiling in patients with breast cancer, using a highly sensitive detection system.Semantic proximity Read ↗

Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors.Semantic proximity Read ↗

Detection of PIK3CA hotspot mutations in canine mammary tumors using droplet digital PCR: tissue validation and liquid biopsy feasibility.Semantic proximity Read ↗

Intertumor and intratumor heterogeneity of PIK3CA mutations in extramammary Paget's disease.Semantic proximity Read ↗

Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.