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Article

Use of Liquid Biopsy to Detect PIK3CA Mutation in Metastatic Breast Cancer.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi - 11 Mar 2022

Nakai Maki, Yamada Takeshi, Sekiya Kenta, Sato Ai, Hankyo Meishi, Kuriyama Sho, Takahashi Goro, Kurita Tomoko, Yanagihara Keiko, Yoshida Hiroshi, Ohashi Ryuji, Takei Hiroyuki

Abstract excerpt

BACKGROUND: PIK3CA is associated with tumor progression, and the prevalence of PIK3CA mutation is high in breast cancer. Liquid biopsy offers convenient, noninvasive, and real-time insight into genetic alteration. In this study, we used liquid biopsy to detect PIK3CA mutations in patients with breast cancer. METHODS: We recruited patients with histologically confirmed breast cancer and distant metastases between...

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PMID: 33692304
DOI: 10.1272/jnms.JNMS.2022_89-107

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