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Article

Frequency of genetic alterations differs in advanced breast cancer between metastatic sites.

Genes, chromosomes & cancer - 1 Jan 2024

Grote Isabel, Poppe Alexandra, Lehmann Ulrich, Christgen Matthias, Kreipe Hans, Bartels Stephan

Abstract excerpt

About 20%-30% of breast cancer (BC) patients will develop distant metastases, preferentially in bones, liver, lung, and brain. BCs with different intrinsic subtypes prefer different sites for metastasis. These subtypes vary in the abundance of genetic alterations which may influence the localization of metastases. Currently, information about the relation between metastatic site and mutational profile of BC is...

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Identifiers

PMID: 37672607
DOI: 10.1002/gcc.23199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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