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Article

Potential Pleiotropic Genes and Shared Biological Pathways in Epilepsy and Depression Based on GWAS Summary Statistics.

Computational intelligence and neuroscience - 1 Jan 2022

Lin Han, Lin Wan-Hui, Lin Feng, Liu Chang-Yun, Che Chun-Hui, Huang Hua-Pin

Abstract excerpt

Current epidemiological and experimental studies have indicated the overlapping genetic foundation of epilepsy and depression. However, the detailed pleiotropic genetic etiology and neurobiological pathways have not been well understood, and there are many variants with underestimated effect on the comorbidity of the two diseases. Utilizing genome-wide association study (GWAS) summary statistics of epilepsy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35463244
DOI: 10.1155/2022/6799285
PMCID: PMC9019309

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