Article

Comprehensive analysis of genetic risk loci uncovers novel candidate genes and pathways in the comorbidity between depression and Alzheimer’s disease

2023-02-10

Abstract excerpt

<title>Abstract</title> <p>As there is growing evidence of shared pathogenesis between Alzheimer’s disease and depression, we aimed to further investigate the shared disease mechanisms of these highly comorbid disorders using brain-specific eQTL data and gene co-expression networks of genetic loci significantly associated with Alzheimer’s disease and depression. We found no identical GWAS SNPs between Alzheimer’s...

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Literature Corpus work: 85f47921-2e73-5f6f-b9f9-abd51a433139
DOI: 10.21203/rs.3.rs-2556408/v1

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