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Article

Identify novel, shared and disorder-specific genetic architecture of major depressive disorder, insomnia and chronic pain.

Journal of psychiatric research - 1 Nov 2022

Zheng Haohao, Sun Jie, Pang Tao, Liu Jiajia, Lu Lin, Chang Suhua

Abstract excerpt

Major depressive disorder (MDD), insomnia (INS) and chronic pain (CP) often have high comorbidity and show high genetic correlation. Here we aimed to better characterize their novel, shared and disorder-specific genetic architecture. Based on genome-wide association study (GWAS) summary data, we applied the conditional false discovery rate (condFDR) and conjunctional FDR (conjFDR) approach to investigate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 36191519
DOI: 10.1016/j.jpsychires.2022.09.036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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