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Article

Multivariate analysis of genome-wide data to identify potential pleiotropic genes for five major psychiatric disorders using MetaCCA.

Journal of affective disorders - 1 Jan 2019

Jia XiaoCan, Yang YongLi, Chen YuanCheng, Cheng ZhiWei, Du Yuhui, Xia Zhenhua, Zhang Weiping, Xu Chao, Zhang Qiang, Xia Xin, Deng HongWen, Shi XueZhong

Abstract excerpt

BACKGROUND: Genome-wide association studies have been extensively applied in identifying SNP associated with major psychiatric disorders. However, the SNPs identified by the prevailing univariate approach only explain a small percentage of the genetic variance of traits, and the extensive data have shown the major psychiatric disorders have common biological mechanisms and the overlapping pathophysiological...

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Source

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Identifiers

PMID: 30212762
DOI: 10.1016/j.jad.2018.07.046
PMCID: PMC6343670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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