Article
Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia.
Science China. Life sciences - 1 Jan 2022
Wang He, Yi Zhenghui, Shi Tieliu
Abstract excerpt
Different psychiatric disorders share genetic relationships and pleiotropic loci to certain extent. We integrated and analyzed datasets related to major depressive disorder (MDD), bipolar disorder (BIP), and schizophrenia (SCZ) from the Psychiatric Genomics Consortium using multitrait analysis of genome-wide association analysis (MTAG). MTAG significantly increased the effective sample size from 99,773 to 119,754...
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