Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pediatric High Grade Glioma Classification Criteria and Molecular Features of a Case Series

31 Mar 2022

Abstract excerpt

Pediatric high-grade gliomas (pHGGs) encompass a heterogeneous group of tumors. Three main molecular types (H3.3 mutant, IDH mutant, and H3.3/IDH wild-type) and a number of subtypes have been identified. We provide an overview of pHGGs and present a mono-institutional series. We studied eleven non-related pHGG samples through a combined approach of routine diagnostic tools and a gene panel. TP53 and H3F3A were...

Topics

Join the communities discussing this publication.

Glioma Diagnosis and Treatment
Neuroblastoma Research and Treatments
Sarcoma Diagnosis and Treatment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35456430
DOI: 10.3390/genes13040624

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pediatric High Grade Glioma Classification Criteria and Molecular Features of a Case SeriesPMID 35456430Read ↗

Pediatric Hemispheric High-Grade Gliomas and H3.3-G34 Mutation: A Review of the Literature on Biological Features and New Therapeutic Strategies.Semantic proximity Read ↗

Paediatric type diffuse high grade gliomas in the WHO CNS5 classification: What the pathologist needs to know?Semantic proximity Read ↗

Epigenetic programming of pediatric high-grade glioma: Pushing beyond proof of concept to clinical benefitSemantic proximity Read ↗

The Spectrum of IDH- and H3-Wildtype High-Grade Glioma Subgroups Occurring across Teenage and Young Adult Patient PopulationsSemantic proximity Read ↗

Recent Advances on the Molecular Pathology of Glial Neoplasms in Children and Adults.Semantic proximity Read ↗

H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers.Semantic proximity Read ↗

Gliomas in children and adolescents: investigation of molecular alterations with a potential prognostic and therapeutic impact.Semantic proximity Read ↗

Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures.Semantic proximity Read ↗

Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.Semantic proximity Read ↗

Cancer Predisposition Syndromes Associated With Pediatric High-Grade GliomasSemantic proximity Read ↗

Molecular Genetics and Targeted Therapies for Paediatric High-grade GliomaSemantic proximity Read ↗

Significance of H3K27M mutation with specific histomorphological features and associated molecular alterations in pediatric high-grade glial tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.