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Article

Molecular Genetics and Targeted Therapies for Paediatric High-grade Glioma

1 Jan 2022

Abstract excerpt

Brain tumours are the leading cause of paediatric cancer-associated death worldwide. High-grade glioma (HGG) represents a main cause of paediatric brain tumours and is associated with poor prognosis despite surgical and chemoradiotherapeutic advances. The molecular genetics of paediatric HGG (pHGG) are distinct from those in adults, and therefore, adult clinical trial data cannot be extrapolated to children....

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PMID: 35732328
DOI: 10.21873/cgp.20328

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