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Article

Recent Advances on the Molecular Pathology of Glial Neoplasms in Children and Adults.

The Journal of molecular diagnostics : JMD - 1 Sept 2016

Rodriguez Fausto J, Vizcaino M Adelita, Lin Ming-Tseh

Abstract excerpt

Gliomas represent the most common primary intraparenchymal tumors of the central nervous system in adults and children and are a genetic and phenotypic heterogeneous group. Large multi-institutional studies and The Cancer Genome Atlas have provided firm insights into the basic genetic drivers in gliomas. The main molecular biomarkers routinely applied to evaluate diffuse gliomas include MGMT promoter methylation,...

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Source

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Identifiers

PMID: 27444975
DOI: 10.1016/j.jmoldx.2016.05.005
PMCID: PMC5397677

Genes

ATRX
BRAF
EGFR
FGFR1
IDH1
IDH2
MGMT
MYB
MYBL1
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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