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Article

The relationship between childhood abuse and dissociation. Is it influenced by catechol-O-methyltransferase (COMT) activity?

The international journal of neuropsychopharmacology - 1 Mar 2008

Savitz Jonathan B, van der Merwe Lize, Newman Timothy K, Solms Mark, Stein Dan J, Ramesar Rajkumar S

Abstract excerpt

Dissociation is a failure of perceptual, memorial and emotional integration that is associated with a variety of psychiatric disorders. Dissociative processes are usually attributed to the sequelae of childhood trauma although there are data to suggest that genetic influences are also important. Bipolar disorder (BD), a condition with a strong genetic basis, has also been associated with early psychological...

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Identifiers

PMID: 17608961
DOI: 10.1017/S1461145707007900

Genes

COMT
BDNF
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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