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Article

Multidrug Resistance-1 C3435T Polymorphism and Carbamazepine Plasma Level in Indonesian Temporal Lobe Epilepsy Patients.

Current drug safety - 1 Jan 2023

Budikayanti Astri, Khosama Herlyani, Octaviana Fitri, Hamid Donny H, Louisa Melva, Ranakusuma Teguh A S, Setiabudy Rianto

Abstract excerpt

BACKGROUND: Temporal lobe epilepsy (TLE) has the highest probability of becoming resistant. One of the causes was Polymorphism in multidrug resistant-1 (MDR1) C3435T. In Dr. Cipto Mangunkusumo Hospital, potential drug-resistant epilepsy prevalence was 84.51%; 66.6% of them used carbamazepine (CBZ) as antiseizure medication. This comparative cross-sectional study aimed to investigate MDR1 C3435T polymorphism and...

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Identifiers

PMID: 35430998
DOI: 10.2174/1574886317666220414130526
PMCID: PMC10009892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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