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Article

Significance of MDR1 gene polymorphism C3435T in predicting drug response in epilepsy.

Epilepsy research - 1 Feb 2014

Shaheen Uzma, Prasad D K V, Sharma Vandana, Suryaprabha T, Ahuja Y R, Jyothy A, Munshi Anjana

Abstract excerpt

Antiepileptic drug (AED) treatment in epilepsy is often compromised by the unpredictability of efficacy and inter-individual variability among patients, which at least in part is the result of genetic variation. The idea to determine an individual's response to a prescribed medicine came into inception around 29 years ago. Pharmacogenetics is used to predict the drug response and efficacy, as well as potential...

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PMID: 24300029
DOI: 10.1016/j.eplepsyres.2013.11.009

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