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Article

Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey.

European neurology - 1 Jan 2008

Ozgon Gulay Oner, Bebek Nerses, Gul Gunay, Cine Naci

Abstract excerpt

BACKGROUND AND AIMS: We investigated the prevalence of this multidrug resistance 1 gene (MDR1) polymorphism in drug-responsive versus drug-resistant epilepsy patients treated with carbamazepine (CBZ), which is a substrate of this protein. METHODS: We genotyped the C3435T variant of MDR1 in 97 patients treated with CBZ monotherapy who had been on stable doses for more than 1 month. Our control group included 174...

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Source

Identifiers

PMID: 17917461
DOI: 10.1159/000109264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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