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Systematic analysis of inflammation and pain pathways in a mouse model of gout

16 Apr 2022

Abstract excerpt

Gout is a prevalent and painful inflammatory arthritis, and its global burden continues to rise. Intense pain induced by gout attacks is a major complication of gout. However, systematic studies of gout inflammation and pain are lacking. Using a monosodium urate (MSU) crystal-induced gout model, we performed genome-wide transcriptome analysis of the inflamed ankle joint, dorsal root ganglion (DRG), and spinal...

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PMID: 35430901
DOI: 10.1177/17448069221097760

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