Article
Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese.
Nature communications - 13 May 2015
Li Changgui, Li Zhiqiang, Liu Shiguo, Wang Can, Han Lin, Cui Lingling, Zhou Jingguo, Zou Hejian, Liu Zhen, Chen Jianhua, Cheng Xiaoyu, Zhou Zhaowei, Ding Chengcheng, Wang Meng, Chen Tong, Cui Ying, He Hongmei, Zhang Keke, Yin Congcong, Wang Yunlong, Xing Shichao, Li Baojie, Ji Jue, Jia Zhaotong, Ma Lidan, Niu Jiapeng, Xin Ying, Liu Tian, Chu Nan, Yu Qing, Ren Wei, Wang Xuefeng, Zhang Aiqing, Sun Yuping, Wang Haili, Lu Jie, Li Yuanyuan, Qing Yufeng, Chen Gang, Wang Yangang, Zhou Li, Niu Haitao, Liang Jun, Dong Qian, Li Xinde, Mi Qing-Sheng, Shi Yongyong
Abstract excerpt
Gout is one of the most common types of inflammatory arthritis, caused by the deposition of monosodium urate crystals in and around the joints. Previous genome-wide association studies (GWASs) have identified many genetic loci associated with raised serum urate concentrations. However, hyperuricemia alone is not sufficient for the development of gout arthritis. Here we conduct a multistage GWAS in Han Chinese...
Topics
Join the communities discussing this publication.