Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.

European journal of cancer (Oxford, England : 1990) - 1 Jun 2022

Lyskjær Iben, Kara Neesha, De Noon Solange, Davies Christopher, Rocha Ana Maia, Strobl Anna-Christina, Usher Inga, Gerrand Craig, Strauss Sandra J, Schrimpf Daniel, von Deimling Andreas, Beck Stephan, Flanagan Adrienne M

Abstract excerpt

AIM: Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Circulating free (cfDNA) and circulating tumour DNA (ctDNA) are promising biomarkers for disease surveillance and prognostication in several cancer types; however, few such studies are reported for OS. The purpose of this study was to discover and validate methylation-based biomarkers to detect plasma ctDNA in patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Genomics and Diagnostics

Share to Circulating Tumor DNA

Share to Mutation

Share to Osteosarcoma

Share to Prognosis

Source

Identifiers

PMID: 35421838
DOI: 10.1016/j.ejca.2022.03.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.PMID 35421838Read ↗

Osteosarcoma: novel prognostic biomarkers using circulating and cell-free tumour DNASemantic proximity Read ↗

5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease status in patients with osteosarcomaSemantic proximity Read ↗

Clinical insights into circulating free-DNA in patients with bone sarcomas and ewing sarcoma.Semantic proximity Read ↗

Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomasSemantic proximity Read ↗

Osteosarcoma: Integrating Epidemiological Insights, Genomic Advances, Environmental Determinants, and Novel Therapeutic Strategies in Contemporary Oncological PracticeSemantic proximity Read ↗

Circulating tumour-derived DNA in metastatic soft tissue sarcomaSemantic proximity Read ↗

Circulating tumor DNA as prognostic markers for late stage NSCLC with bone metastasis.Semantic proximity Read ↗

Epigenetic patterns and methylation-based models for robust outcome prediction in osteosarcomaSemantic proximity Read ↗

Decoding CTCs in osteosarcoma: the molecular journey from initial tumor to metastasis.Semantic proximity Read ↗

Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcomaSemantic proximity Read ↗

Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in osteosarcomaSemantic proximity Read ↗

Profiling targetable immune checkpoints in osteosarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.