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Article

Clinical insights into circulating free-DNA in patients with bone sarcomas and ewing sarcoma.

Clinics (Sao Paulo, Brazil) - 1 Jan 2025

Aran Veronica, Santos Cavalcanti Amanda, Meohas Walter, Canteri Bruna, Perini Jamila Alessandra, Pino Minguez Jesus, Guimarães João Antônio Matheus, Moura Neto Vivaldo, Leite Duarte Maria Eugênia

Abstract excerpt

BACKGROUND AND OBJECTIVES: Sarcomas represent a heterogeneous group of malignancies characterized by varying clinical behaviors and treatment responses. Liquid biopsy has emerged as a promising non-invasive method for monitoring tumor dynamics by detecting actionable mutations in cancer patients. The emergence of circulating DNA as a non-invasive biomarker offers promising avenues for improving diagnostic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40288045
DOI: 10.1016/j.clinsp.2025.100661
PMCID: PMC12059349

Genes

IDH2
TP53

Variants

Provenance

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