Article

Epigenetic patterns and methylation-based models for robust outcome prediction in osteosarcoma

2025-11-20

Abstract excerpt

<h4>ABSTRACT</h4> Osteosarcoma (OSA) is an aggressive bone malignancy primarily affecting children and young adults. Survival has remained unchanged for at least three decades, and no robust molecular prognostic factors have emerged that might help improve this outcome. Complex genomic architecture and genetic heterogeneity of OSA have constrained identification and validation of such molecular predictors. Recent...

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Literature Corpus work: 652fc3fa-6436-5d21-b6ce-733e944d020f
DOI: 10.1101/2025.11.19.25340108

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