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Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomas

1 Sept 2021

Abstract excerpt

Aims Cell-free DNA (cfDNA) and circulating tumour DNA (ctDNA) are used for prognostication and monitoring in patients with carcinomas, but their utility is unclear in sarcomas. The objectives of this pilot study were to explore the prognostic significance of cfDNA and investigate whether tumour-specific alterations can be detected in the circulation of sarcoma patients. Methods Matched tumour and blood were...

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PMID: 34558310
DOI: 10.1302/2046-3758.109.bjr-2021-0014.r1

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