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Article

Epitope characterization of a monoclonal antibody that selectively recognizes KIR2DL1 allotypes.

HLA - 1 Aug 2022

Falco Michela, Meazza Raffaella, Alicata Claudia, Canevali Paolo, Muntasell Aura, Bottino Cristina, Moretta Lorenzo, Pende Daniela, Lopez-Botet Miguel

Abstract excerpt

Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating receptors, finely tuning NK cell function. Numerous studies reported the relevance of KIR allelic polymorphism on KIR expression, ligand affinity, and strength in signal transduction. Although KIR variability, including gene copy number and allelic polymorphism, in combination with HLA class I polymorphism, impacts both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35411634
DOI: 10.1111/tan.14630
PMCID: PMC9544867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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