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Article

Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2007

Estefanía Ernesto, Flores Raquel, Gómez-Lozano Natalia, Aguilar Helena, López-Botet Miguel, Vilches Carlos

Abstract excerpt

Human NK cells, by means of a repertoire of clonally distributed killer cell Ig-like receptors (KIR), survey the expression of individual self HLA class I molecules, which is often altered in infections and tumors. KIR2DL5 (CD158f) is the last identified KIR gene and, with KIR2DL4, constitutes a structurally divergent lineage conserved in different primate species. Research on KIR2DL5 has thus far been limited to...

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PMID: 17371997
DOI: 10.4049/jimmunol.178.7.4402

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Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets.PMID 17371997Read ↗

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