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Lung Transplant in a Patient With Multifocal Langerhans Cell Histiocytosis After Chemotherapy With Cladribine: A Case Report.

Transplantation proceedings - 1 May 2022

Abba Mary Ene, Żegleń Sławomir, Łącka Monika, Maruszewski Marcin, Kowalski Jacek, Stachowicz-Chojnacka Kamila, Wojarski Jacek, Ulatowski Nikodem, Karolak Wojciech

Abstract excerpt

Langerhans cell histiocytosis (LCH) is a rare inflammatory disorder of myeloid dendritic cells with mutations involving KRAS, BRAF and/or NRAS, and MAP2K1 genes. We describe the case of a 58-year-old female previous smoker with multifocal LCH involving the lungs, pituitary gland and mandibular bone. Initial treatment with 6 cycles of cladribine showed improvement in her extrapulmonary lesions, however, her lung...

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PMID: 35410720
DOI: 10.1016/j.transproceed.2022.02.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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