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[Reaserch Advance on Langerhans Cell Histiocytosis Review].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2020

Fan Zhi-Qiao, Pan Yao-Zhu, Liu Ping, Fan Wen-Jing, Bai Hai

Abstract excerpt

Abstract　　Langerhans cell histiocytosis (LCH) is a disease originated from bone marrow dendritic cells, and classified as a tumor by the discovery of a recurrent somatic BRAF-V600E point mutation in the RAS-RAF-MEK-ERK signaling pathway. The clinical manifestations of LCH are mainly granulomatous lesions composed of clonal pathological tissue cells. According to the lesions and invasive risk organs, it is divided...

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Identifiers

PMID: 32027303
DOI: 10.19746/j.cnki.issn.1009-2137.2020.01.060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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