Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy.

doi:10.1111/bjh.19462

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Article

Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy.

British journal of haematology - 1 Jul 2024

Friedman Joshua S, Durham Benjamin H, Reiner Anne S, Yabe Mariko, Petrova-Drus Kseniya, Dogan Ahmet, Pulitzer Melissa, Busam Klaus J, Francis Jasmine H, Rampal Raajit K, Ulaner Gary A, Reddy Ryan, Yeh Randy, Hatzoglou Vaios, Lacouture Mario E, Rotemberg Veronica, Mazor Roei D, Hershkovitz-Rokah Oshrat, Shpilberg Ofer, Goyal Gaurav, Go Ronald S, Abeykoon Jithma P, Rech Karen, Morlote Diana, Fidai Shiraz, Gannamani Vedavyas, Zia Maryam, Abdel-Wahab Omar, Panageas Katherine S, Rosenblum Marc K, Diamond Eli L

Abstract excerpt

Histiocytic neoplasms are diverse clonal haematopoietic disorders, and clinical disease is mediated by tumorous infiltration as well as uncontrolled systemic inflammation. Individual subtypes include Langerhans cell histiocytosis (LCH), Rosai-Dorfman-Destombes disease (RDD) and Erdheim-Chester disease (ECD), and these have been characterized with respect to clinical phenotypes, driver mutations and treatment...

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Identifiers

PMID: 38613141
DOI: 10.1111/bjh.19462
PMCID: PMC11245369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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