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Article

The Mutation of CD27 Deficiency Presented With Familial Hodgkin Lymphoma and a Review of the Literature.

Journal of pediatric hematology/oncology - 1 May 2022

Köse Doğan, Güzelçiçek Ahmet, Öz Özlem, Erdem Arzu Y, Haliloğlu Yeşim, Witzel Maximilian, Klein Christoph, Ünal Ekrem

Abstract excerpt

This study aimed to report 4 siblings with CD27 deficiency presented with Hodgkin lymphoma. The father of the family, his 2 wives, and 17 children born from these wives were included into the study. CD27 mutation of all the family members with, and without Hodgkin lymphoma were studied. The variants detected by the exome sequencing analysis were verified by Sanger sequencing and analyzed using SeqScape Software...

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Identifiers

PMID: 35398861
DOI: 10.1097/MPH.0000000000002453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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