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Article

CTLA4 haploinsufficiency as a predisposition to classical Hodgkin lymphoma.

Pediatric hematology and oncology - 1 Mar 2020

Mahat Upendra, Terzioglu Meryem K, Buhtoiarov Ilia

Abstract excerpt

Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) haploinsufficiency (HI) is an immune dysregulation disorder characterized by T lymphocyte hyperactivation, and generalized lymphoproliferative and autoimmune disorders. Patients with CTLA4 haploinsufficiency are also prone to developing various malignancies. Due to the rare nature of this condition, the longitudinal evolution of CTLA4 haploinsufficiency clinical...

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Identifiers

PMID: 31971458
DOI: 10.1080/08880018.2019.1710310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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