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Article

Association of CD27 and CD70 gene polymorphisms with risk of sporadic breast cancer in Chinese women in Heilongjiang Province.

Breast cancer research and treatment - 1 Jun 2012

Xu Fengyan, Li Dalin, Zhang Qiujin, Fu Zhenkun, Yuan Weiguang, Pang Da, Li Dianjun

Abstract excerpt

CD27 and its ligand, CD70, are major costimulatory molecules whose interaction can regulate the expansion and differentiation of effector and memory T-cell populations. Their abnormal expression can disturb the immune response and lead to an increased risk of cancer. This study aims to evaluate the associations between single nucleotide polymorphisms (SNPs) in CD27/CD70 gene and breast cancer susceptibility. Five...

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PMID: 22399187
DOI: 10.1007/s10549-012-1987-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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