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Article

Lymphoma Predisposing Gene in an Extended Family: CD70 Signaling Defect.

Journal of clinical immunology - 1 Aug 2020

Khodzhaev Khusan, Bay Sema Buyukkapu, Kebudi Rejin, Altindirek Didem, Kaya Aysenur, Erbilgin Yucel, Ng Ozden Hatirnaz, Kiykim Ayca, Erol Funda Cipe, Zengin Feride Sen, Firtina Sinem, Ng Yuk Yin, Aksoy Basak Adakli, Sayitoglu Muge

Abstract excerpt

Genome-wide sequencing studies in pediatric cancer cohorts indicate that about 10% of patients have germline mutations within cancer predisposition genes. Within this group, primary immune deficiencies take the priority regarding the vulnerability of the patients to infectious agents and the difficulties of cancer management. On the other hand, early recognition of these diseases may offer specific targeted...

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PMID: 32620996
DOI: 10.1007/s10875-020-00816-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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