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Article

Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27.

Haematologica - 1 Mar 2013

Salzer Elisabeth, Daschkey Svenja, Choo Sharon, Gombert Michael, Santos-Valente Elisangela, Ginzel Sebastian, Schwendinger Martina, Haas Oskar A, Fritsch Gerhard, Pickl Winfried F, Förster-Waldl Elisabeth, Borkhardt Arndt, Boztug Kaan, Bienemann Kirsten, Seidel Markus G

Abstract excerpt

CD27, a tumor necrosis factor receptor family member, interacts with CD70 and influences T-, B- and NK-cell functions. Disturbance of this axis impairs immunity and memory generation against viruses including Epstein Barr virus (EBV), influenza, and others. CD27 is commonly used as marker of memo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22801960
DOI: 10.3324/haematol.2012.068791
PMCID: PMC3659923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22801960-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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