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[Application of next-generation sequencing in detection of BRCA1/2 and homologous recombination repair pathway multi-genes germline mutation and correlation analysis].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 6 Mar 2022

Chen Y L, Zhuo Z L, Liu C, Xie F, Yang Z Y, Liu P F, Wang S, Zhao X T

Abstract excerpt

Objective: To investigate the germline mutation status of related genes in breast cancer patients and high-risk individuals by next-generation sequencing. To analyze the correlations between homologous recombination repair (HR) pathway gene mutation status and clinicopathological characteristics of breast cancer patients. To supplement the database of breast cancer related gene mutations in Chinese population....

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Identifiers

PMID: 35381651
DOI: 10.3760/cma.j.cn112150-20211208-01132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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