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Article

Regulation of ISWI involves inhibitory modules antagonized by nucleosomal epitopes.

Nature - 13 Dec 2012

Clapier Cedric R, Cairns Bradley R

Abstract excerpt

Chromatin-remodelling complexes (CRCs) mobilize nucleosomes to mediate the access of DNA-binding factors to their sites in vivo. These CRCs contain a catalytic subunit that bears an ATPase/DNA-translocase domain and flanking regions that bind nucleosomal epitopes. A central question is whether and how these flanking regions regulate ATP hydrolysis or the coupling of hydrolysis to DNA translocation, to affect...

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Identifiers

PMID: 23143334
DOI: 10.1038/nature11625
PMCID: PMC3631562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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