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FURIN gene variants (rs6224/rs4702) as potential markers of death and cardiovascular traits in severe COVID‐19

30 Mar 2022

Abstract excerpt

Furin is a protease that plays a key role in the infection cycle of SARS-CoV-2 by cleaving the viral proteins during the virus particle assembly. In addition, Furin regulates several physiological processes related to cardio-metabolic traits. DNA variants in the FURIN gene are candidates to regulate the risk of developing these traits as well as the susceptibility to severe COVID-19. We genotyped two functional...

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PMID: 35355278
DOI: 10.1002/jmv.27748

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