Back to search

Article

Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populations

2023-01-03

Abstract excerpt

<h4>Background: </h4> SARS CoV-2, the causative agent for the ongoing COVID-19 pandemic, enters the host cell by activating the ACE2 receptor with the help of two proteases, i.e., Furin and TMPRSS2. Therefore, variations in these genes may account for differential susceptibility and severity between populations. Our previous studies have shown that ACE2 and TMPRSS2 gene variants are essential in understanding COVI...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a1689fb4-df5e-5276-9ddb-db7321008595
DOI
10.21203/rs.3.rs-2385490/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populationsDOI 10.21203/rs.3.rs-2385490/v1
ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19Semantic proximity
A comprehensive germline variant and expression analyses of <i>ACE2</i> , <i>TMPRSS2</i> and SARS-CoV-2 activator <i>FURIN</i> genes from the Middle East: Combating SARS-CoV-2 with precision medicineSemantic proximity
Assessing COVID-19 Susceptibility Through Analysis of the Genetic and Epigenetic Diversity of ACE2-Mediated SARS-CoV-2 EntrySemantic proximity
Genetic association of TMPRSS2 rs2070788 polymorphism with COVID-19 case fatality rate among Indian populations.Semantic proximity
Genetic polymorphisms and expression of SARS-CoV-2 host entry genes associate with COVID-19 severity in an unvaccinated Moroccan cohort.Semantic proximity
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene VariantsSemantic proximity
Genetic variability in COVID-19-related genes in the Brazilian populationSemantic proximity
Host genetic basis of COVID-19: from methodologies to genesSemantic proximity
Genetic association of <i>TMPRSS2</i> rs2070788 polymorphism with COVID-19 Case Fatality Rate among Indian populationsSemantic proximity
Bioinformatics Analysis of Allele Frequencies and Expression Patterns of ACE2, TMPRSS2 and FURIN in Different Populations and Susceptibility to SARS-CoV-2.Semantic proximity
Genetic variability in COVID-19-related genes in the Brazilian populationSemantic proximity
Integrative Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization Reveal Risk Loci for Long COVIDSemantic proximity
Select a neighboring publication to make it the new centre.