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COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2

1 Jan 2021

Abstract excerpt

Furin is a proprotein convertase that activates different kinds of regulatory proteins, including SARS-CoV-2 spike protein which contains an additional furin-specific cleavage site. It is essential in predicting cancer patients' susceptibility to SARS-CoV-2 and the disease outcomes due to varying furin expressions in tumor tissues. In this study, we analyzed furin's expression, methylation, mutation rate,...

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PMID: 34671211
DOI: 10.7150/ijbs.63072

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