Article
Diagnostic utility of BNP, corin and furin as biomarkers for cardiovascular complications in type 2 diabetes mellitus patients.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2015
Fathy Shadia A, Abdel Hamid Fatma F, Zabut Baker M, Jamee Amal F, Ali Mohamed A M, Abu Mustafa Ayman M
Abstract excerpt
CONTEXT: The number of patients with type 2 diabetes mellitus (T2DM) is progressively increasing, and diabetic cardiovascular complications have become a public health problem. Brain or B-type natriuretic peptide (BNP) is a cardiac hormone synthesized as a pre-pro-peptide. pro-BNP is produced by cleaving the signal peptide then two proprotein convertases, corin and furin cleave pro-BNP to form a biologically...
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