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Article

Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population.

BMC medical genetics - 11 Oct 2011

Fang Qiurong, Zhao Hailing, Wang Aihua, Gong Yaoqin, Liu Qiji

Abstract excerpt

BACKGROUND: Genome-wide association studies of asthma have identified a novel region containing ORMDL3 at chromosome 17q21 that is strongly associated with childhood-onset asthma and significantly linked to ORMDL3 transcript abundance. These results have been successfully replicated in childhood-onset asthma cohorts in several ethnic groups. In this study, we aimed to evaluate the association of polymorphisms in...

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Source

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Identifiers

PMID: 21985515
DOI: 10.1186/1471-2350-12-133
PMCID: PMC3207945

Genes

ORMDL3
GSDMB
IKZF3
ZPBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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