Article
HLA-DRA Gene Polymorphisms Are Associated with Graves' Disease as an Autoimmune Thyroid Disease.
BioMed research international - 1 Jan 2022
Du Peng, Zhu Jiaoli, Yao Qiuming, Cai Tiantian, Xu Jianbin, Fang Yudie, Wu Yuqing, Zhang Wen, Zhang Jin-An
Abstract excerpt
Background: Autoimmune thyroid disease (AITD), one of the most prevalent organ-specific autoimmune diseases, mainly includes Graves' disease (GD) and Hashimoto's thyroiditis (HT). This study was aimed at researching the association between AITD and single nucleotide polymorphisms (SNPs) of the HLA-DRA gene. Methods: Using Hi-SNP high-throughput sequencing technology, we detected the distribution of three SNPs...
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