Article
Investigation on the association between NLRP3 gene polymorphisms and susceptibility to primary gout.
Genetics and molecular research : GMR - 9 Dec 2015
Wang L F, Ding Y J, Zhao Q, Zhang X L
Abstract excerpt
We conducted a case-control study to investigate the association between 3 common NALP3 polymorphisms (rs10754558, rs7512998, and rs12137901) and the susceptibility to primary gout. A total of 320 patients with primary gout and 320 controls were included in this study. The genotyping of NALP3 rs10754558, rs7512998, and rs12137901 were conducted by polymerase chain reaction-restriction fragment length...