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Article

A GWAS in Idiopathic/Unexplained Infertile Men Detects a Genomic Region Determining Follicle-Stimulating Hormone Levels.

The Journal of clinical endocrinology and metabolism - 14 Jul 2022

Schubert Maria, Pérez Lanuza Lina, Wöste Marius, Dugas Martin, Carmona F David, Palomino-Morales Rogelio J, Rassam Yousif, Heilmann-Heimbach Stefanie, Tüttelmann Frank, Kliesch Sabine, Gromoll Jörg

Abstract excerpt

CONTEXT: Approximately 70% of infertile men are diagnosed with idiopathic (abnormal semen parameters) or unexplained (normozoospermia) infertility, with the common feature of lacking etiologic factors. Follicle-stimulating hormone (FSH) is essential for initiation and maintenance of spermatogenesis. Certain single-nucleotide variations (SNVs; formerly single-nucleotide polymorphisms [SNPs]) (ie, FSHB c.-211G > T,...

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Identifiers

PMID: 35305013
DOI: 10.1210/clinem/dgac165
PMCID: PMC9282256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A GWAS in Idiopathic/Unexplained Infertile Men Detects a Genomic Region Determining Follicle-Stimulating Hormone Levels.PMID 35305013Read ↗

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